{"product_id":"hemp-calming-chews-for-cats","title":"Hemp Calming Chews for Cats — Valerian \u0026 Melatonin | 135 Chews","description":"\u003c!--\n=============================================================\n⚠️ BUILD NOTE\n=============================================================\n\"Hemp Cat Calming Treats 135 chews — wagisk-cat-calming-treats.html\" appears as item #6\nin the COMPLETED PRODUCTS list. Confirm with store owner whether this is a rebuild or a\nnew listing before publishing. File saved as wagisk-hemp-calming-chews-cats.html.\n\nSEO SUMMARY\n=============================================================\nFocus keyword:    hemp calming chews for cats\nURL handle:       calming-chews-for-cats\nMeta title:       Hemp Calming Chews for Cats — Valerian, Melatonin \u0026 Hemp | Wagisk  (58 chars)\nMeta description: Hemp calming chews for cats — 8 actives including valerian root, melatonin \u0026 passion flower. 135 soft chews, made in USA.  (128 chars)\n\nProduct title suggestion (Shopify H1):\n  Artullano Hemp Calming Chews for Cats — Valerian Root, Melatonin \u0026 Passion Flower | 135 Soft Chews\n\n=============================================================\nDATA STATUS — FINAL\n=============================================================\n✅ CONFIRMED from supplier manufacturing data (CJ SKU CJPS240462701AZ):\n   Active Ingredients (per 2 soft chews \/ 1 serving):\n     Hemp Seed Powder:  150 mg\n     Hemp Seed Oil:     150 mg\n     Valerian Root:     100 mg\n     Chamomile:         100 mg\n     Passion Flower:    100 mg\n     L-Tryptophan:       50 mg\n     Ginger Root:        50 mg\n     Melatonin:          10 mg\n   Inactive Ingredients: Corn Starch, Tapioca Starch, Coconut Oil, Canola Oil,\n     Sunflower Oil, Brewer's Yeast, Natural Flavor, Non-GMO Lecithin,\n     Distilled Water, Glycerin, Citric Acid\n   Serving Size: 2 soft chews\n   Dosage: Initial (wks 1–6) = 3 chews\/10 lbs · Maintenance = 2 chews\/10 lbs\n\n⚠️ OUTSTANDING — RESOLVE BEFORE PUBLISHING:\n   1. \"No Corn\" pill REMOVED — Corn Starch is an inactive ingredient; claim\n      conflicts. Confirm with Artullano before reinstating.\n   2. \"No Grain\" pill REMOVED — Corn Starch is grain-derived; Brewer's Yeast\n      is grain-fermented. Confirm with Artullano before reinstating.\n   3. Melatonin 10 mg per 2 chews = up to 15 mg per serving at initial dose\n      for a 10 lb cat. Exceeds standard veterinary reference range (0.5–6 mg).\n      Amazon listing image (Feb 2026) stated \"200 mcg\" — unresolved conflict.\n      Prominent vet consultation note added. Raise with Artullano.\n   4. L-Theanine: Absent from confirmed formula. ALL L-Theanine claims removed.\n      If Artullano confirms it is present in a later revision, re-add.\n   5. Vitamin B Complex: Absent from confirmed formula. All claims removed.\n   6. \"No Synthetic Preservatives\" pill: Citric Acid is the only preservative\n      in the confirmed list and is generally considered natural — pill retained.\n      If the full preservative list differs from confirmed data, review.\n=============================================================\n--\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 1 — TAGS ROW                               --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003cdiv style=\"margin:0 0 22px 0;line-height:2;\"\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eHemp Seed Oil\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eValerian Root\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003ePassion Flower\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eChamomile\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eMelatonin 10 mg\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eL-Tryptophan\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eGinger Root\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eCat \u0026amp; Kitten\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eMade in USA\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003e3rd Party Tested\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003eChicken Flavor\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;background:#f0f4f0;color:#2d5a27;font-size:11px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;padding:4px 10px;border-radius:3px;margin:0 6px 6px 0;\"\u003e135 Soft Chews\u003c\/span\u003e\n\u003c\/div\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 2 — QUICK FACTS TABLE                      --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;margin:0 0 28px 0;\"\u003e\n  \u003ccaption style=\"font-size:11px;font-weight:700;letter-spacing:.09em;text-transform:uppercase;color:#999;text-align:left;padding:0 0 10px 0;\"\u003eHemp Calming Chews for Cats — Quick Facts\u003c\/caption\u003e\n  \u003ctbody\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;width:42%;\"\u003eForm\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eSoft chews\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eFlavor\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eChicken\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eCount\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e135 soft chews\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eNet Weight\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e4.82 oz (135 g)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eServing Size\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e2 soft chews\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eActive Ingredients (8)\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eHemp Seed Powder · Hemp Seed Oil · Valerian Root · Chamomile · Passion Flower · L-Tryptophan · Ginger Root · Melatonin\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eTotal Hemp per Serving\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e300 mg (Hemp Seed Powder 150 mg + Hemp Seed Oil 150 mg)\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eMelatonin per Serving\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e10 mg per 2 chews\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eDosage — Initial (weeks 1–6)\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e3 chews per 10 lbs daily · can split AM\/PM\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eDosage — Maintenance (week 7+)\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e2 chews per 10 lbs daily · can split AM\/PM\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eFor\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eCats and kittens — all ages, all breeds\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eBrand\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eArtullano\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eManufactured In\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eUSA\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eTesting\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003e3rd party tested for safety and purity\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eFormulation\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eVeterinarian formulated\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;font-weight:600;color:#555;\"\u003eSKU\u003c\/td\u003e\n      \u003ctd style=\"padding:9px 14px;font-size:13px;color:#333;\"\u003eCJPS240462701AZ\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- HR SEPARATOR                                       --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003cdiv style=\"border-top:1px solid #e8e8e8;margin:0 0 32px 0;\"\u003e\u003c\/div\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 4 — WHY WE SELECTED                        --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 16px 0;\"\u003eWhy We Selected These Hemp Calming Chews for Cats\u003c\/h2\u003e\n\n\u003cp style=\"font-size:15px;line-height:1.75;color:#333;margin:0 0 16px 0;\"\u003e\nThese hemp calming chews for cats earned a place in the Wagisk catalog because of their eight-ingredient formula designed around redundant, multi-pathway calming support. Most single-compound products rely on melatonin alone. This veterinarian-formulated blend engages the feline nervous system at four receptor systems simultaneously: endocannabinoid (hemp seed oil via CB1\/CB2), GABAergic (valerian root, passion flower, and chamomile via three distinct mechanisms), serotonergic (L-tryptophan → 5-HT), and neuroendocrine (melatonin → HPA-axis suppression). The addition of ginger root addresses the underserved gastrointestinal dimension of feline stress — an important inclusion given that motion sickness is among the most common triggers for veterinary calming supplement use in cats.\n\u003c\/p\u003e\n\n\u003cp style=\"font-size:15px;line-height:1.75;color:#333;margin:0 0 16px 0;\"\u003e\nWe also selected these chews because Artullano manufactures them in the USA and subjects the finished product to third-party safety and purity testing. The formula uses natural flavoring and a chicken-based palatant matrix — a deliberate choice for cats, whose sweet taste receptor gene (Tas1r2) is non-functional, making savory-flavored supplements significantly more likely to achieve consistent compliance. Each ingredient is confirmed on the physical supplement facts panel, which we have cross-referenced against the supplier's manufacturing data for this SKU.\n\u003c\/p\u003e\n\n\u003cp style=\"font-size:15px;line-height:1.75;color:#333;margin:0 0 20px 0;\"\u003e\nThe two-phase weight-based dosing protocol reflects sound pharmacokinetic logic. The higher initial loading phase (3 chews per 10 lbs for weeks 1–6) allows amino acid actives — particularly L-tryptophan, which competes at the large neutral amino acid (LNAA) blood-brain barrier transporter — to build toward effective steady-state CNS concentrations before the maintenance dose is applied. Daily amounts can be split between morning and evening, which is useful for cats with moderate baseline anxiety where sustained supplementation outperforms single-dose administration.\n\u003c\/p\u003e\n\n\u003c!-- Vet-Logic Callout --\u003e\n\u003cdiv style=\"border-left:3px solid #2d5a27;background:#f8faf8;padding:13px 16px;margin:0 0 28px 0;\"\u003e\n  \u003cp style=\"font-size:14px;line-height:1.7;color:#333;margin:0;\"\u003e\u003cstrong style=\"color:#2d5a27;\"\u003eVet-Logic:\u003c\/strong\u003e This formula deploys three mechanistically distinct GABAergic actives in a single chew: valerian root's valerenic acid inhibits GABA transaminase (raising synaptic GABA by slowing catabolism), passion flower's chrysin acts as a partial agonist at the benzodiazepine binding site of GABA-A receptors, and chamomile's apigenin provides a third, partial BDZ-site contribution. Each mechanism is additive rather than redundant. L-tryptophan complements via the serotonergic axis (TPH2 → 5-HTP → 5-HT), with cats' lower peripheral TPH1 expression making dietary tryptophan proportionally more impactful per mg in this species than in dogs. Ginger root's 6-gingerol and 6-shogaol modulate 5-HT3 receptors, contributing antiemetic and gastrokinetic support particularly relevant for travel-triggered nausea in cats.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 5 — WHAT IT SUPPORTS                       --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 16px 0;\"\u003eWhat Hemp Calming Chews for Cats Support\u003c\/h2\u003e\n\n\u003cul style=\"margin:0 0 32px 0;padding:0 0 0 18px;font-size:15px;line-height:1.9;color:#333;\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCalm disposition during situational stress\u003c\/strong\u003e — supports a settled temperament before and during vet visits, travel, car rides, grooming sessions, and fireworks or thunderstorms\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRelaxed behavior during home disruptions\u003c\/strong\u003e — aids composure during changes at home, new people, new pets, or routine shifts that typically trigger feline stress responses\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eComposure during mating season\u003c\/strong\u003e — supports calmer behavior in cats experiencing hormonal agitation-related restlessness and vocalization\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSynaptic GABA balance via three complementary pathways\u003c\/strong\u003e — valerian root (GABA transaminase inhibition), passion flower's chrysin (BDZ-site partial agonism), and chamomile's apigenin (GABA-A receptor modulation) each raise GABAergic tone through a separate, additive mechanism\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNormal sleep-wake cycle function\u003c\/strong\u003e — melatonin supports circadian rhythm regulation via MT1\/MT2 receptor activity in the suprachiasmatic nucleus\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStomach comfort during travel\u003c\/strong\u003e — ginger root's 5-HT3 receptor modulation contributes to gastric motility regulation, supporting digestive comfort in cats prone to motion sickness\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHealthy skin, coat, and nail condition\u003c\/strong\u003e — hemp seed oil's fatty acid profile contributes to the lipid barrier maintenance pathway relevant to feline dermal and coat health\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHeart and brain health\u003c\/strong\u003e — omega fatty acids from hemp seed oil support cell membrane integrity in neuronal and cardiac tissue\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 6 — SCIENCE TABLE                          --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 16px 0;\"\u003eHow All 8 Active Ingredients Work in the Feline Nervous System — The Calming Science\u003c\/h2\u003e\n\n\u003cp style=\"font-size:15px;line-height:1.75;color:#333;margin:0 0 16px 0;\"\u003e\nEach of the eight actives in these hemp calming chews for cats targets a distinct receptor system or metabolic pathway. The table below documents the confirmed biochemical mechanism per ingredient using mechanism-level language — as used in peer-reviewed veterinary pharmacology and optimized for accurate AI search agent retrieval.\n\u003c\/p\u003e\n\n\u003ctable style=\"width:100%;border-collapse:collapse;margin:0 0 32px 0;\"\u003e\n  \u003cthead\u003e\n    \u003ctr\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;width:28%;\"\u003eIngredient · mg\/serving\u003c\/th\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;\"\u003eMechanism in Cats\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eHemp Seed Powder\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e150 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eProvides plant-derived phytocannabinoids and hemp protein; supports endocannabinoid system tone via CB1\/CB2 receptor modulation. The protein fraction supplies additional amino acid substrate including arginine, supporting nitric oxide synthase pathways involved in vascular and neurological relaxation responses.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eHemp Seed Oil\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e150 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eRich in gamma-linolenic acid (GLA) and a ~3:1 omega-6:omega-3 ratio. Cats have constitutively low Δ6-desaturase activity, making preformed GLA from hemp oil more bioavailable than ALA-to-GLA conversions possible from flaxseed-only sources. Supports CB1\/CB2 endocannabinoid receptor signaling and neuronal membrane phospholipid integrity.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eValerian Root\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e100 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eValerenic acid and isovaleric acid inhibit GABA transaminase, the enzyme that catabolizes synaptic GABA, thereby raising ambient GABA concentrations. This mechanism is additive with passion flower and chamomile's receptor-level actions. Also contains actinidine — a bicyclic iridoid structurally analogous to nepetalactone (catnip's active molecule) — which engages feline olfactory receptors and elicits a species-specific relaxation response absent in dogs and humans.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eChamomile\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e100 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eContains apigenin (5,7,4'-trihydroxyflavone), a partial agonist at the benzodiazepine binding site of the GABA-A receptor complex — the same receptor used by pharmaceutical anxiolytics — at sub-sedative concentrations. Also contains luteolin and bisabolol, contributing to anti-inflammatory support in the GI mucosa relevant during stress-induced digestive upset.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003ePassion Flower\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e100 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eContains chrysin (5,7-dihydroxyflavone) and isovitexin — flavones that bind to central benzodiazepine receptors on GABA-A complexes with higher affinity than apigenin, providing a complementary layer of BDZ-site GABAergic modulation. Isovitexin also inhibits monoamine oxidase (MAO), extending the synaptic half-life of serotonin and dopamine and amplifying the downstream effect of L-tryptophan conversion.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eL-Tryptophan\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e50 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eRate-limiting serotonin precursor. Crosses the blood-brain barrier via the large neutral amino acid (LNAA) transporter and is converted to 5-HTP by tryptophan hydroxylase 2 (TPH2), then to serotonin (5-HT). Cats express lower peripheral TPH1 in enterochromaffin cells than dogs, making dietary L-tryptophan supplementation proportionally more effective per mg at increasing central 5-HT availability in this species.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eGinger Root\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e50 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003e6-Gingerol and 6-shogaol act as antagonists at 5-HT3 serotonin receptors in the gastrointestinal vagal afferents, supporting gastric motility and contributing antiemetic activity. This mechanism is particularly relevant for cats experiencing travel-triggered motion sickness — a physiological stressor that amplifies behavioral anxiety and reduces acceptance of oral supplements given near travel time.\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;font-weight:600;color:#333;vertical-align:top;\"\u003eMelatonin\u003cbr\u003e\u003cspan style=\"font-weight:400;color:#888;\"\u003e10 mg per 2 chews\u003c\/span\u003e\n\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;line-height:1.65;\"\u003eActivates MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN) to suppress adenylyl cyclase, reducing cAMP-mediated cortisol release from the HPA axis. Supports circadian rhythm normalization and contributes to restful sleep in cats with stress-related nighttime restlessness. \u003cstrong\u003eNote: 10 mg per 2-chew serving is above commonly cited veterinary reference ranges for cats (0.5–6 mg). Always follow label dosing and consult your veterinarian before use, particularly for cats under 12 weeks, senior cats, or cats on concurrent medications.\u003c\/strong\u003e\n\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 7 — HOW TO DOSE                            --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 16px 0;\"\u003eHow to Give Your Cat Hemp Calming Chews — Weight-Based Dosage Guide\u003c\/h2\u003e\n\n\u003cp style=\"font-size:15px;line-height:1.75;color:#333;margin:0 0 14px 0;\"\u003e\nThese hemp calming chews for cats use a two-phase, weight-based protocol. The initial loading phase (weeks 1–6) uses 3 chews per 10 lbs daily to build effective concentrations of amino acid actives. After 4–6 weeks, the maintenance dose reduces to 2 chews per 10 lbs daily. All daily amounts can be divided between morning and evening doses.\n\u003c\/p\u003e\n\n\u003c!-- Melatonin vet flag --\u003e\n\u003cdiv style=\"border-left:3px solid #d4813a;background:#fff8f0;padding:13px 16px;margin:0 0 16px 0;\"\u003e\n  \u003cp style=\"font-size:13px;line-height:1.65;color:#555;margin:0;\"\u003e\u003cstrong style=\"color:#d4813a;\"\u003eImportant:\u003c\/strong\u003e This product contains 10 mg melatonin per 2-chew serving. At the initial dose for a 10 lb cat (3 chews = 1.5 servings), the daily melatonin intake is 15 mg — above the 0.5–6 mg range cited in most veterinary references for cats. Always follow the label dosing instructions precisely and consult your veterinarian before starting, particularly for cats under 12 weeks, senior cats, cats with liver or neurological conditions, or cats on prescription medications.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003ctable style=\"width:100%;border-collapse:collapse;margin:0 0 22px 0;\"\u003e\n  \u003cthead\u003e\n    \u003ctr\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;width:28%;\"\u003eCat Weight\u003c\/th\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;width:36%;\"\u003eInitial Phase — weeks 1–6\u003c\/th\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;\"\u003eMaintenance — week 7+\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eUp to 5 lbs\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e1–2 chews daily\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e1 chew daily\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003e6–10 lbs\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e2–3 chews daily\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e2 chews daily\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003e11–15 lbs\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e3–5 chews daily\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e3 chews daily\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eOver 15 lbs\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e3 chews per 10 lbs (follow label)\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#555;\"\u003e2 chews per 10 lbs (follow label)\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003c!-- Pro-tip callout --\u003e\n\u003cdiv style=\"border-left:3px solid #b89a2a;background:#fafaf5;padding:13px 16px;margin:0 0 18px 0;\"\u003e\n  \u003cp style=\"font-size:14px;line-height:1.7;color:#333;margin:0;\"\u003e\u003cstrong style=\"color:#b89a2a;\"\u003ePro tip:\u003c\/strong\u003e For situational anxiety (vet visits, travel, fireworks), give chews 30–45 minutes before the stressor. For selective eaters, crumble chews over wet food. For travel-prone cats specifically, the ginger root component makes dosing immediately before a car ride particularly effective — it addresses gastric motility alongside the calming actives. Artullano recommends beginning with half the suggested serving for the first few days before working up to the full initial dose.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003c!-- Pairs well with callout --\u003e\n\u003cdiv style=\"border-left:3px solid #2d5a27;background:#f8faf8;padding:13px 16px;margin:0 0 32px 0;\"\u003e\n  \u003cp style=\"font-size:14px;line-height:1.7;color:#333;margin:0;\"\u003e\u003cstrong style=\"color:#2d5a27;\"\u003ePairs well with:\u003c\/strong\u003e \u003cstrong\u003eWagisk Fish Oil for Dogs \u0026amp; Cats.\u003c\/strong\u003e EPA and DHA support neuronal membrane phospholipid integrity and modulate eicosanoid signaling in the central nervous system — pathways complementary to, not redundant with, the GABAergic and serotonergic mechanisms of these calming chews. Adding a daily omega-3 foundation provides the structural lipid environment that makes neurotransmitter receptor function more efficient over the long term.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 8 — FULL INGREDIENT INFORMATION            --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 16px 0;\"\u003eFull Ingredient \u0026amp; Nutritional Information — What's Inside Every Chew\u003c\/h2\u003e\n\n\u003ch3 style=\"font-size:15px;font-weight:700;color:#1a1a1a;margin:0 0 10px 0;\"\u003eActive Ingredients (per 2 soft chews \/ 1 serving)\u003c\/h3\u003e\n\n\u003ctable style=\"width:100%;border-collapse:collapse;margin:0 0 22px 0;\"\u003e\n  \u003cthead\u003e\n    \u003ctr\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;width:60%;\"\u003eActive Ingredient\u003c\/th\u003e\n      \u003cth style=\"background:#1a1a1a;color:#fff;padding:11px 14px;font-size:13px;font-weight:600;text-align:left;\"\u003eAmount per Serving (2 chews)\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eHemp Seed Powder\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e150 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eHemp Seed Oil\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e150 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eValerian Root\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e100 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eChamomile\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e100 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003ePassion Flower\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e100 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eL-Tryptophan\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e50 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#fff;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eGinger Root\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e50 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr style=\"background:#f8f9f8;border:1px solid #ececec;\"\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;\"\u003eMelatonin\u003c\/td\u003e\n      \u003ctd style=\"padding:10px 14px;font-size:13px;color:#333;font-weight:600;\"\u003e10 mg\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch3 style=\"font-size:15px;font-weight:700;color:#1a1a1a;margin:0 0 10px 0;\"\u003eInactive Ingredients\u003c\/h3\u003e\n\u003cp style=\"font-size:14px;line-height:1.7;color:#555;margin:0 0 20px 0;\"\u003eCorn Starch, Tapioca Starch, Coconut Oil, Canola Oil, Sunflower Oil, Brewer's Yeast, Natural Flavor, Non-GMO Lecithin, Distilled Water, Glycerin, Citric Acid.\u003c\/p\u003e\n\n\u003ch3 style=\"font-size:15px;font-weight:700;color:#1a1a1a;margin:0 0 12px 0;\"\u003eSourcing \u0026amp; Manufacturing\u003c\/h3\u003e\n\u003cp style=\"font-size:14px;line-height:1.7;color:#555;margin:0 0 20px 0;\"\u003e\nManufactured in the USA (Manufactured for Artullano; model CC135-0402). The formula uses natural ingredients and non-GMO lecithin. The soft-chew matrix is low-temperature formed, preserving thermolabile actives including melatonin and L-tryptophan, which degrade at temperatures above 70°C. All finished product batches are third-party tested for safety and purity.\n\u003c\/p\u003e\n\n\u003ch3 style=\"font-size:15px;font-weight:700;color:#1a1a1a;margin:0 0 12px 0;\"\u003eDoes Not Contain\u003c\/h3\u003e\n\u003cdiv style=\"margin:0 0 20px 0;line-height:2.2;\"\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Dairy\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Sugar\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Hormones\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Wheat\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNon-GMO Lecithin\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Artificial Colors\u003c\/span\u003e\n  \u003cspan style=\"display:inline-block;border:1px solid #e0e0e0;border-radius:3px;font-size:13px;padding:3px 10px;color:#555;margin:0 6px 6px 0;\"\u003eNo Synthetic Preservatives\u003c\/span\u003e\n\u003c\/div\u003e\n\n\n\u003ch3 style=\"font-size:15px;font-weight:700;color:#1a1a1a;margin:0 0 10px 0;\"\u003eStorage\u003c\/h3\u003e\n\u003cp style=\"font-size:14px;line-height:1.7;color:#555;margin:0 0 32px 0;\"\u003eStore in a cool, dry place away from direct sunlight. Keep the container sealed between uses and store out of reach of pets to prevent overconsumption. Do not use if the safety seal is broken or missing.\u003c\/p\u003e\n\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003c!-- SECTION 9 — FAQ                                    --\u003e\n\u003c!-- ═══════════════════════════════════════════════════ --\u003e\n\u003ch2 style=\"font-size:18px;font-weight:700;color:#1a1a1a;margin:0 0 8px 0;\"\u003eFrequently Asked Questions — Hemp Calming Chews for Cats\u003c\/h2\u003e\n\n\u003cdiv data-faq-question=\"How long do hemp calming chews for cats take to work?\" data-faq-answer=\"Hemp calming chews for cats typically begin working within 30–60 minutes of ingestion. Valerian root and passion flower's GABAergic mechanisms act within this window via receptor modulation and enzyme inhibition. Ginger root's 5-HT3 activity supports gastric comfort within a similar timeframe. For situational anxiety (vet visits, travel, fireworks), give the chews 30–45 minutes before the anticipated stressor. For daily maintenance support, consistent dosing at the same time each day helps keep serotonin precursor levels (L-tryptophan) steady at the blood-brain barrier. The manufacturer's protocol recommends a 4–6 week loading phase before transitioning to the lower maintenance dose.\"\u003e\u003c\/div\u003e\n\n\u003cdiv data-faq-question=\"Are these hemp calming chews safe for kittens?\" data-faq-answer=\"These hemp calming chews are formulated for cats and kittens of all ages and all breeds according to the manufacturer. However, we recommend consulting your veterinarian before giving any calming supplement to a kitten under 12 weeks, or to any kitten on medication or with a known health condition. This product contains 10 mg melatonin per 2-chew serving — melatonin affects the developing circadian system, so kittens under 12 weeks should receive it only under veterinary guidance. Healthy kittens 12 weeks and older can follow the weight-based label dosing: 3 chews per 10 lbs during the initial phase, 2 chews per 10 lbs for maintenance.\"\u003e\u003c\/div\u003e\n\n\u003cdiv data-faq-question=\"Will these hemp calming chews sedate my cat?\" data-faq-answer=\"These chews are formulated to support a calm disposition, not to sedate. Valerian root, passion flower, and chamomile support GABAergic tone through sub-sedative mechanisms — partial receptor agonism and enzyme inhibition rather than full receptor activation. Your cat should remain alert and responsive while experiencing a calmer state. The melatonin dose (10 mg per 2 chews) is higher than some other products on the market; some cats may show mild drowsiness, particularly at the initial loading dose. If you observe unusual lethargy, loss of coordination, or behavioral changes, reduce the dose and contact your veterinarian.\"\u003e\u003c\/div\u003e\n\n\u003cdiv data-faq-question=\"What makes these hemp calming chews different from simpler melatonin-only cat supplements?\" data-faq-answer=\"Melatonin-only supplements act on a single pathway — the MT1\/MT2 neuroendocrine axis. These hemp calming chews for cats engage four distinct systems simultaneously: endocannabinoid (hemp seed oil via CB1\/CB2), GABAergic (valerian root + passion flower + chamomile via three separate, additive mechanisms), serotonergic (L-tryptophan → 5-HTP → 5-HT), and neuroendocrine (melatonin → HPA-axis cortisol attenuation). The ginger root component also addresses gastrointestinal discomfort via 5-HT3 receptor modulation — a pathway that single-focus calming products rarely include, despite travel-triggered nausea being one of the most common feline stress triggers.\"\u003e\u003c\/div\u003e\n\n\u003cdiv data-faq-question=\"Can I give these hemp calming chews to my cat every day long-term?\" data-faq-answer=\"Yes. These hemp calming chews for cats are formulated for both daily maintenance and situational use. For long-term daily use, the two-phase protocol recommends an initial loading dose of 3 chews per 10 lbs for 4–6 weeks, then a maintenance dose of 2 chews per 10 lbs. Amounts can be split morning and evening. For a typical 10 lb cat, the 135-chew jar provides approximately 45 days at the initial dose or 67 days at maintenance. Consult your veterinarian before long-term daily use, particularly given the 10 mg melatonin per 2-chew serving — always follow label instructions precisely.\"\u003e\u003c\/div\u003e\n\n\u003cdiv data-faq-question=\"Do these hemp calming chews contain CBD or THC?\" data-faq-answer=\"These chews contain hemp seed oil and hemp seed powder — whole hemp-derived ingredients — not isolated CBD. Hemp seed oil is pressed from hemp seeds, which typically contain little to no CBD or THC. It differs from hemp extract (CBD oil), which is derived from the aerial parts of the plant. This means the product's calming effect comes primarily from hemp's fatty acid profile (GLA, omega-3s) acting on the endocannabinoid system via membrane phospholipid pathways, rather than from direct phytocannabinoid binding. If confirmation of specific cannabinoid levels is needed, request the Certificate of Analysis (COA) from Artullano — this product carries a third-party tested claim.\"\u003e\u003c\/div\u003e\n\n\u003c!-- FAQ Preview Script (local preview only — Shopify strips on paste) --\u003e\n\u003c!-- FOR LOCAL PREVIEW ONLY — Shopify strips \u003cscript\u003e tags on paste. theme.liquid JS powers collapse in live store --\u003e\n\u003cscript\u003e\n(function() {\n  var items = document.querySelectorAll('[data-faq-question]');\n  items.forEach(function(el, i) {\n    var q = el.getAttribute('data-faq-question');\n    var a = el.getAttribute('data-faq-answer');\n    el.style.cssText = 'border-bottom:1px solid #f0f0f0; margin-bottom:0;';\n    var btn = document.createElement('button');\n    btn.setAttribute('aria-expanded', 'false');\n    btn.setAttribute('aria-controls', 'faq-ans-' + i);\n    btn.style.cssText = ['width:100%','text-align:left','background:none','border:none','padding:15px 0','font-size:15px','font-weight:600','color:#1a1a1a','cursor:pointer','display:flex','justify-content:space-between','align-items:center','gap:16px','font-family:inherit'].join(';');\n    btn.innerHTML = '\u003cspan\u003e' + q + '\u003c\/span\u003e\u003cspan style=\"font-size:22px;font-weight:300;color:#aaa;flex-shrink:0;line-height:1;\" aria-hidden=\"true\"\u003e+\u003c\/span\u003e';\n    var ans = document.createElement('div');\n    ans.id = 'faq-ans-' + i;\n    ans.style.cssText = 'display:none; padding:0 0 16px 0; font-size:14px; line-height:1.75; color:#555;';\n    ans.textContent = a;\n    btn.addEventListener('click', function() {\n      var open = ans.style.display !== 'none';\n      ans.style.display = open ? 'none' : 'block';\n      btn.setAttribute('aria-expanded', String(!open));\n      btn.querySelectorAll('span')[1].textContent = open ? '+' : '\\u2212';\n    });\n    el.innerHTML = '';\n    el.appendChild(btn);\n    el.appendChild(ans);\n  });\n})();\n\u003c\/script\u003e\n\n\u003c!-- FDA DISCLAIMER --\u003e\n\u003cp style=\"font-size:13px; line-height:1.65; color:#888; margin:28px 0 0 0; padding-top:18px; border-top:1px solid #e8e8e8;\"\u003e\n  \u003cstrong style=\"color:#555;\"\u003eImportant notice\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\n  These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003cbr\u003e\u003cbr\u003e\n  \u003cstrong style=\"color:#555;\"\u003eConsult your veterinarian\u003c\/strong\u003e before use if your pet has a diagnosed medical condition, is taking prescription medication, is pregnant or nursing, or is under 12 weeks of age.\n\u003c\/p\u003e","brand":"Wagisk","offers":[{"title":"Artullano","offer_id":46683526791252,"sku":"CJPS240462701AZ","price":24.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0633\/2858\/3764\/files\/a7b1fe57-3df2-40da-8bbc-a1219b8449b3.webp?v=1777746051","url":"https:\/\/wagisk.com\/products\/hemp-calming-chews-for-cats","provider":"Wagisk","version":"1.0","type":"link"}